TECHNOLOGY
Engineering Biology with Precision
Accubiotas develops human-relevant New Approach Methodologies (NAMs) by combining microengineering, advanced biological models, and quantitative measurement technologies.
From Biological Models to Quantitative Insights
Accubiotas develops engineered biological systems that combine relevant cellular models, controlled microenvironments, and quantitative measurement. The goal is to create research platforms that provide more informative and measurable biological data for preclinical research.
01 MODEL
Human-relevant biological systems
02 MEASURE
Quantitative and real-time measurements
03 ANALYZE
Data-driven biological interpretation
Core Technologies
Microengineering
Organ-on-a-Chip
Microengineered platforms designed to recreate relevant cellular and physiological environments in controlled in vitro systems.
Barrier Models
BBB-on-a-Chip
A three-dimensional blood-brain barrier model designed to study barrier function and drug responses under controlled conditions.
Monitoring
Real-Time TEER
Quantitative measurement of barrier integrity through real-time trans-endothelial electrical resistance monitoring.
Advanced Platforms
3D Platforms Spheroid&Organoid
3D cellular and spheroid-based platforms supporting controlled biological research and experimental workflows.
FEATURED TECHNOLOGY
BBB-on-a-Chip
A quantitative platform for studying blood-brain barrier function and drug responses.
Accubiotas' BBB-on-a-Chip platform integrates three-dimensional cell culture, controlled fluidic flow, endothelial cell–astrocyte co-culture, and real-time TEER measurement.
3D Cellular Architecture
Controlled Fluidic Flow
Endothelial–Astrocyte Co-culture
Real-Time TEER Measurement
HOW THE PLATFORM WORKS
From Biological Model to Quantitative Insight
Accubiotas combines engineered biological environments with quantitative measurements to study barrier function and biological responses under controlled in vitro conditions.
STEP 01
Cellular Model
Use relevant endothelial cells and astrocytes to establish a biologically meaningful BBB model.
STEP 02
3D Culture & Flow
Maintain the cellular model within a three-dimensional microfluidic environment with controlled fluidic flow.
STEP 03
Barrier Monitoring
Monitor barrier integrity quantitatively using real-time TEER measurement.
STEP 04
Experimental Response
Evaluate changes in barrier function and biological responses under experimental conditions.
Measure What Matters
REAL-TIME TEER
Barrier integrity is a critical parameter in blood-brain barrier research. Accubiotas integrates real-time TEER measurement to quantitatively monitor changes in barrier integrity during experiments.
FEATURE 01
Quantitative Measurement
Real-time TEER provides a quantitative measure of barrier integrity during an experiment.
FEATURE 02
Continuous Monitoring
Monitor changes in barrier properties over the course of experimental conditions rather than relying only on endpoint observations.
FEATURE 03
Experimental Insight
Use quantitative barrier measurements to support interpretation of biological responses and experimental outcomes.
From biological structure to measurable function.